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SweatScope: 2-Electrode Biochemical Sensing Board

Nov 2025
SweatScope: 2-Electrode Biochemical Sensing Board

Description

In my lab, I made a four-layer ESP32-based electrochemical impedance spectroscopy (EIS) board designed for on-body, multi-ion sweat analysis. The system generates controlled AC excitation signals ranging from 20 to 200 kHz and measures the resulting impedance of the sweat sample using a two-electrode EIS configuration. By analyzing the impedance response, the device can estimate the concentrations of key sweat constituents, including NaCl, KCl, urea, and sodium lactate. The board integrates an ESP32 microcontroller for real-time data acquisition, signal processing, and wireless communication, and includes a built-in display for visualizing Nyquist plots and frequency-response characteristics directly on the device. Mentor: Nikita Lukhanin

Technologies

PCB Design
Mixed-Signal
Chemistry

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